Ankle pumps
Lie on your back or sit. Pull your toes up towards you, then point them down. During time spent in bed, this works the calf muscles and stops the ankle from stiffening.
10–15 repetitions, several times a dayRehabilitation guide
Guillain-Barré syndrome is a rare condition in which the immune system attacks the peripheral nerves, and it needs urgent treatment in hospital. Weakness progresses over days and weeks, then slowly returns: most people walk within six months and recover within a year. During recovery, physiotherapy is the foundation of regaining strength and independence.
The immune system attacks the nerves outside the brain and spinal cord; the nerves cannot carry signals to the muscles and from the senses. It most often starts a few weeks after an infection such as flu or a stomach bug. It can occur at any age; it is more common in adults and in males.
Weakness progresses over hours, days or weeks; nine out of ten patients have reached their weakest point by the third week. Then recovery begins.
Treatment takes place in hospital and usually lasts several weeks. One of two methods is used to stop the immune system attacking the nerves: intravenous immunoglobulin (IVIG) or plasma exchange. According to the Cochrane review, in severely affected patients IVIG started within the first two weeks speeds recovery about as much as plasma exchange; giving the two one after the other brings no extra benefit.
Alongside this, breathing, heart rate and blood pressure are closely monitored; ventilator support is given if needed. In patients who cannot walk, medicines and compression stockings are used to prevent blood clots in the leg veins, and medicines are used for nerve pain.
According to a 2025 review of 16 studies, exercise after Guillain-Barré may increase strength, reduce fatigue and support independence; however, the studies are small and the authors state that larger research is needed. Keep sessions short and rest in between; if you have marked fatigue or increased weakness the next day, ease the programme.
Exercises at home
These exercises are for the period after leaving hospital and are ordered from easier to harder. Which step you are on depends on your strength; decide your programme with your physiotherapist, and stop before you are tired out.
Lie on your back or sit. Pull your toes up towards you, then point them down. During time spent in bed, this works the calf muscles and stops the ankle from stiffening.
10–15 repetitions, several times a dayLie on your back with a rolled-up towel under your knee. Press the back of your knee into the towel to tighten the muscle at the front of your thigh, hold for a few seconds and relax.
Hold for 5 seconds, 10 repetitionsLie on your back with your knees bent. Slowly lift your hips, hold for a moment and lower with control. Stop when you are tired; quality matters more than numbers.
5–10 repsSit towards the front of a sturdy chair. Lean forwards and stand up, using your hands for support as much as you need, then sit down slowly. As you get stronger, use your hands less.
5–10 reps, 1–2 setsStand upright holding onto a worktop. Lift both heels together and lower slowly. Ankle strength is often the last to return; work at it patiently.
8–10 repsTake short walks spread through the day instead of one long walk. Use a walking frame or stick if needed. If you have marked fatigue or weakness the next day, reduce the distance.
Several times a day, building up little by littleVideo
From the YouTube channel of Mayo Clinic in the USA.
A radio interview about Guillain-Barré syndrome.
Most people recover fully, including those who were severely affected. In some people, however, weakness, numbness, fatigue or pain can last a long time. Recovery can take anywhere from a few weeks to a few years; that is why rehabilitation and regular follow-up matter.
Most people walk within six months and recover within a year. Weakness usually reaches its worst within the first two to four weeks, then slowly returns. The time varies a great deal from person to person; strength may not return to every muscle at the same rate.
It can; that is why follow-up is recommended every few months after recovery at first, and then once a year. If your long-term symptoms get worse, or symptoms return after you have recovered, contact your specialist without waiting.
The research available suggests exercise may be helpful: according to a 2025 review of 16 studies, exercise may increase strength, reduce fatigue and support independence. Even so, the studies are small and not enough to be certain. Adjust your programme with your physiotherapist, according to your fatigue.
Get help without waiting in the following situations:
Sources